Back around 1860 it was known as the Fred Sheets home at 6th & Main. If you collect Wellsville memorabilia you have probably seen F.O. Sheets Photography on some of those old post cards.
Today it is the home of Central Federal Bank. There's been a lot of changes made but the original building is easily recognized when comparing the two.
The old photograph is on display in the Wellsville Room of the River Museum.